Statines and fibrates

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Pages: 106
ISBN : 2-7420-0279-0
Printed in: French

In recent years, considerable advances have been made in the prevention and treatment of myocardial infarctus through the medical use of statines, which sharply reduce cholesterol levels and thus the risk of cardiovascular disease. This innovation also highlighted the major part played by hypercholesterolemia in coronary pathology.
Fibrates, which form part of a different pharmaceutical group, are now used in the treatment of hypertriglyceridemia, which is also involved in vascular disorders.
And now research is being carried out into the possibility of combining statines and fibrates to treat resistant pathologies.
This fascinating work, edited by one of France's leading specialists in cardiovascular disease, also describes the first steps being taken towards a new branch of medicine. It describes the short-term uses of this arsenal of cutting-edge -- yet conventional -- drugs, statines-fibrates, and goes on to discuss the progress being made by research into long-term approaches involving new therapeutic concepts using genes, and thus gene therapy.
The years to come will no doubt see a revolution in the therapeutic approach to cardiovascular diseases, which are among the most common complaints in the industrialized world. Some gene deficiencies may be corrected by gene therapy, and the medical use of tailored molecules will no doubt considerably slow the development of atherosclerosis.
This book gives a careful and precise description of the beginnings of this medicine of the future.